منابع مشابه
Can active components of licorice, glycyrrhizin and glycyrrhetinic acid, lick rheumatoid arthritis?
OBJECTIVES This review stated the possible application of the active components of licorice, glycyrrhizin (GL) and glycyrrhetinic acid (GA), in rheumatoid arthritis (RA) treatment based on the cyclooxygenase (COX)-2/thromboxane A2 (TxA2) pathway. METHODS The extensive literature from inception to July 2015 was searched in PubMed central, and relevant reports were identified according to the p...
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The New England Journal of Medicine published the results of the National polyp surveillance (NPS) study in reference to colon cancer mortality among patients with colonic adenomas [1]. This is a prospective study of 2,602 patients who were enrolled from 1980 to 1990 to undergo colonoscopy and followed up for a median time of 15.8 years, with a maximum of 23 years. Only higher-risk patients wer...
متن کاملDownregulation of CRKL expression can inhibit tumorigenesis in colon cancer.
CRKL, as a "switch" factor on several oncogenic pathways, plays vital roles in multiple cancers. However, little is known about CRKL in gastrointestinal cancers. Here, we showed that CRKL is involved in colon cancer, which is the most common form of cancer of the digestive system. Immunohistochemistry analysis showed that CRKL expression in colon tumor tissue is significantly higher than normal...
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C olorectal cancer exhibits a low incidence in under-developed countries even though it is the third most common neoplasm worldwide and the second most common in the U.S. (1, 2). This geographical imbalance suggests an environmental contribution to the resistance of endemic populations to intestinal neoplasia. Although the epidemiology of colon cancer remains poorly understood, there is clearly...
متن کاملColon Cancer
The colon is a part of the large intestine and measures 1.2 meters. The glands lining the inner wall of the colon are the sites for most abnormal cell behavior such as uncontrolled cell growth, which results in polyps (non-cancerous growths) and later on in adenocarcinomas or tumors. The tumors deprive the normal surrounding tissues of nutrients and oxygen and can spread to the lymph nodes in t...
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ژورنال
عنوان ژورنال: Journal of Clinical Investigation
سال: 2009
ISSN: 0021-9738
DOI: 10.1172/jci38936